Pharmacology · single question

A patient's medication list includes omeprazole. What class of drug is omeprazole?

  1. H2 receptor antagonist
  2. Proton pump inhibitor (PPI)
  3. Antacid
  4. Anticholinergic
Show answer and explanation

Correct answer: B. Proton pump inhibitor (PPI)

Omeprazole (Prilosec) is a proton pump inhibitor (PPI). PPIs irreversibly inhibit the H+/K+ ATPase (proton pump) on the apical surface of gastric parietal cells, reducing gastric acid secretion. They are used to treat GERD, peptic ulcer disease, H. pylori eradication, and Zollinger-Ellison syndrome. Other PPIs include lansoprazole, pantoprazole, esomeprazole, and rabeprazole. Dental relevance: long-term PPI use may be associated with dental erosion (from reduced acid buffering), and some PPIs can interact with antiplatelet drugs like clopidogrel (through CYP2C19 inhibition).

Practice Pharmacology questions Pharmacology study notes

More Pharmacology practice questions