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Pharmacology · single question

How many days should apixaban (Eliquis) be discontinued before an elective dental surgical procedure?

  1. 7 days
  2. 1 day (24 hours)
  3. 2 days (48 hours)
  4. 5 days
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Correct answer: C. 2 days (48 hours)

Current guidelines: discontinue apixaban 2 days (48 hours) before dental surgical procedures. Source confirms '2 días.' Note: for NON-traumatic procedures, apixaban does NOT need to be stopped ('no es obligado puedes hacer una eso no traumatic'). Half-life 8–15 hours; 2 days provides adequate washout.
  • A. 7 days is excessive for apixaban — unnecessarily increases thromboembolic risk.
  • B. 1 day (24h) may be insufficient given apixaban's half-life and individual factors.
  • C. CORRECT. 2 days (48 hours) = recommended apixaban interruption before dental surgery. No interruption for non-traumatic procedures.
  • D. 5 days is the recommendation for WARFARIN washout — not apixaban.

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