Same patient with Candida denture stomatitis. What is the best treatment?

Correct answer: B. Systemic antibiotics

• A. Incorrect. Systemic antifungals are reserved for immunocompromised patients with severe or recurrent infection. First-line for denture stomatitis is topical.
• B. Correct. Topical antifungal (nystatin rinse or clotrimazole troches) is the first-line treatment for denture stomatitis. The denture must also be soaked in antifungal solution.
• C. Incorrect. Chlorhexidine has some antifungal properties but is not the primary treatment for Candida denture stomatitis.
• D. Incorrect. Antibiotics treat bacterial infections and are not appropriate for fungal denture stomatitis.

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