A patient with rheumatoid arthritis taking methotrexate is at increased risk for which complication related to this medication?

Methotrexate's immunosuppressive properties (used therapeutically to control autoimmune inflammation in rheumatoid arthritis) increase a patient's susceptibility to infection — an important consideration for dental treatment planning, particularly before invasive procedures, alongside methotrexate's other recognized toxicities (oral ulceration, hepatotoxicity, and renal-clearance-dependent toxicity risk).