Pharmacology · single question
What is the mechanism of action of apixaban (Eliquis)?
Show answer and explanation
Correct answer: C. Direct factor Xa inhibitor
Apixaban is a direct, selective factor Xa inhibitor that reversibly binds factor Xa, reducing thrombin generation.
- A. ❌ Heparin works via antithrombin III; apixaban is a direct oral anticoagulant.
- B. ❌ Vitamin K antagonists include warfarin; apixaban does not affect vitamin K.
- C. ✅ CORRECT – Apixaban is a direct, reversible factor Xa inhibitor.
- D. ❌ Direct thrombin inhibitors include dabigatran; apixaban targets factor Xa.