Micro & Immunology · single question

Which immunoglobulin is predominantly found in saliva?

  1. IgA (secretory IgA — sIgA)
  2. IgG
  3. IgM
  4. IgE
Show answer and explanation

Correct answer: A. IgA (secretory IgA — sIgA)

  • A. Correct. Secretory IgA (sIgA) is the predominant immunoglobulin in saliva and other mucosal secretions, providing first-line mucosal immune defense.
  • B. IgG is the predominant immunoglobulin in serum/blood, not saliva.
  • C. IgM is the first antibody produced in a primary immune response (mainly in blood), not the predominant salivary immunoglobulin.
  • D. IgE is associated with allergic reactions and is not the predominant salivary immunoglobulin.

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