Micro & Immunology · single question
Clindamycin has activity against all of the following EXCEPT:
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Correct answer: A. Pseudomonas aeruginosa
✓ A) Pseudomonas aeruginosa is the EXCEPTION — clindamycin does NOT cover it.
Clindamycin (lincosamide antibiotic) covers: gram-positive cocci (MRSA in some cases), anaerobes (Bacteroides, Fusobacterium, Prevotella — key for dental infections). It does NOT cover aerobic gram-negative rods, especially Pseudomonas aeruginosa. P. aeruginosa requires antipseudomonal agents (piperacillin-tazobactam, ceftazidime, ciprofloxacin, aminoglycosides). This makes clindamycin appropriate for dental/oral anaerobic infections but not for Pseudomonas infections.
Clindamycin (lincosamide antibiotic) covers: gram-positive cocci (MRSA in some cases), anaerobes (Bacteroides, Fusobacterium, Prevotella — key for dental infections). It does NOT cover aerobic gram-negative rods, especially Pseudomonas aeruginosa. P. aeruginosa requires antipseudomonal agents (piperacillin-tazobactam, ceftazidime, ciprofloxacin, aminoglycosides). This makes clindamycin appropriate for dental/oral anaerobic infections but not for Pseudomonas infections.
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