Micro & Immunology · single question

Shingles (herpes zoster) is caused by reactivation of:

  1. HSV-1 (HHV-1)
  2. Cytomegalovirus (HHV-5)
  3. Epstein-Barr virus (HHV-4)
  4. Varicella-zoster virus (HHV-3)
Show answer and explanation

Correct answer: D. Varicella-zoster virus (HHV-3)

Shingles = reactivation of VZV (HHV-3) from dorsal root/trigeminal ganglia where it lay latent after primary chickenpox infection. Reactivation follows a dermatome distribution.

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