Micro & Immunology · single question
Which immunoglobulin is responsible for humoral response in allergies?
Show answer and explanation
Correct answer: A. IgE
✓ A) IgE is correct.
IgE is the primary immunoglobulin involved in Type I (immediate) hypersensitivity reactions, including allergies and anaphylaxis. It binds to mast cells and basophils; upon re-exposure to an allergen, cross-linking of IgE triggers degranulation and histamine release.
✗ IgG mediates secondary immune responses and opsonization. IgM is the first antibody produced in a primary response. T cells are part of cell-mediated (not humoral) immunity.
IgE is the primary immunoglobulin involved in Type I (immediate) hypersensitivity reactions, including allergies and anaphylaxis. It binds to mast cells and basophils; upon re-exposure to an allergen, cross-linking of IgE triggers degranulation and histamine release.
✗ IgG mediates secondary immune responses and opsonization. IgM is the first antibody produced in a primary response. T cells are part of cell-mediated (not humoral) immunity.
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