Pathology · single question

Which disease may clinically resemble or coexist with pemphigus vulgaris?

  1. Pemphigus (other variants)
  2. Mucous membrane pemphigoid
  3. Lichen planus
  4. Ulcerative stomatitis
Show answer and explanation

Correct answer: B. Mucous membrane pemphigoid

  • A. Listing 'pemphigus' as a separate look-alike to pemphigus vulgaris is circular.
  • B. Correct (keyed). Mucous membrane (cicatricial) pemphigoid is the classic vesiculobullous mimic — overlapping desquamative gingivitis/oral erosions, distinguished by DIF.
  • C. Erosive lichen planus can also mimic it; a defensible alternative, but the keyed answer is pemphigoid.
  • D. Ulcerative stomatitis is non-specific.

Note: Erosive lichen planus is also a reasonable mimic; the keyed answer here is mucous membrane pemphigoid.

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