Pathology · single question

Koplik spots are pathognomonic for which infection?

  1. Scarlet fever
  2. Rubella (German measles)
  3. Varicella (chickenpox)
  4. Measles (rubeola)
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Correct answer: D. Measles (rubeola)

  • A. Scarlet fever (group A Streptococcus) causes strawberry tongue and pharyngitis, not Koplik spots.
  • B. Rubella (German measles) produces a forchheimer sign (petechiae on soft palate) but NOT Koplik spots.
  • C. Varicella causes oral vesicles/ulcers but not Koplik spots.
  • D. Correct. Koplik spots — white, grain-of-sand–like spots on the buccal mucosa opposite the first molars — are pathognomonic for measles (rubeola). They appear 1–2 days before the classic morbilliform skin rash.

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