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Pharmacology · single question

What is the most commonly used topical anesthetic in dentistry, and what important FDA safety consideration applies to it?

  1. Benzocaine; the FDA has warned about a rare but serious risk of methemoglobinemia, particularly in young children
  2. Lidocaine; no specific FDA safety warnings exist for topical use
  3. Bupivacaine; commonly used topically with no particular safety concerns
  4. Articaine; primarily used topically with no injectable form available
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Correct answer: A. Benzocaine; the FDA has warned about a rare but serious risk of methemoglobinemia, particularly in young children

Benzocaine is the most commonly used topical anesthetic in dentistry. The FDA has issued safety warnings regarding a rare but serious risk of methemoglobinemia (a condition impairing the blood's oxygen-carrying capacity) associated with benzocaine use, with particular caution advised in young children and infants.

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