Pharmacology · single question
Which of the following is classified as a topical ester local anesthetic commonly used in dentistry?
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Correct answer: A. Benzocaine
Benzocaine is the most commonly used topical ester local anesthetic in dentistry. It is available in gels, sprays, and liquids at concentrations of 7.5% to 20% and is used to anesthetize the oral mucosa before needle injections. As an ester anesthetic, it is metabolized by plasma pseudocholinesterase to PABA (para-aminobenzoic acid), which can cause allergic reactions in sensitive patients. In contrast, mepivacaine and prilocaine are amide local anesthetics. Tetracaine is also an ester but is less commonly used as a topical dental anesthetic in current practice compared to benzocaine.