Pharmacology · single question

A patient who took antibiotics one week ago has GI upset. Most likely explanation?

  1. Developing antibiotic resistance
  2. Disruption of normal GI flora
  3. Hepatotoxicity
  4. Allergic reaction
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Correct answer: B. Disruption of normal GI flora

Disruption of normal GI flora is the most common cause of antibiotic-associated GI upset (antibiotic-associated diarrhea).
  • A. ❌ Antibiotic resistance is a population-level concern; does not explain individual GI upset.
  • B. ✅ CORRECT – Antibiotics disturb the gut microbiome, causing dysbiosis and GI symptoms.
  • C. ❌ Hepatotoxicity presents with jaundice and elevated liver enzymes.
  • D. ❌ Allergic reactions typically present with rash or urticaria.

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