Pharmacology · single question
Amoxicillin has clinically significant drug interactions with all of the following EXCEPT:
Show answer and explanation
Correct answer: A. Analgesics (e.g., acetaminophen/NSAIDs)
✓ A) Analgesics is the EXCEPTION — no significant interaction.
Amoxicillin does not have a clinically significant interaction with common analgesics (acetaminophen, NSAIDs, opioids). Known interactions include: Warfarin (increased INR), oral contraceptives (reduced efficacy — controversial), methotrexate (reduced renal elimination), allopurinol (increased rash risk), and probenecid (reduced amoxicillin clearance).
Amoxicillin does not have a clinically significant interaction with common analgesics (acetaminophen, NSAIDs, opioids). Known interactions include: Warfarin (increased INR), oral contraceptives (reduced efficacy — controversial), methotrexate (reduced renal elimination), allopurinol (increased rash risk), and probenecid (reduced amoxicillin clearance).