Pharmacology · single question

A patient has gingival enlargement shown in a picture. Which medication MOST likely caused this?

  1. Phenytoin (Dilantin)
  2. Lisinopril
  3. Cyclosporine
  4. Nifedipine
Show answer and explanation

Correct answer: A. Phenytoin (Dilantin)

Drug-induced gingival enlargement (DIGO) is classically caused by: phenytoin (Dilantin) for seizures, cyclosporine (immunosuppressant), and calcium channel blockers (nifedipine, amlodipine). Phenytoin is the classic board answer. Lisinopril causes dry cough and angioedema, not gingival enlargement. Phenytoin = most classic DIGO medication.

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