Pharmacology · single question
A child with herpetic gingivostomatitis is brought to the dentist. Which medication should specifically be AVOIDED in this patient?
Show answer and explanation
Correct answer: B. Aspirin
Aspirin must be avoided in children with viral infections (including herpetic gingivostomatitis) due to the risk of Reye's syndrome — a rare but life-threatening condition involving acute hepatic failure and encephalopathy. This risk applies to all viral illnesses in children under 18. Acyclovir is appropriate treatment. Ibuprofen and acetaminophen are safe alternatives for pain/fever management.
- A. ❌ Acyclovir is the appropriate antiviral treatment for herpetic gingivostomatitis.
- B. ✅ CORRECT – Aspirin is absolutely contraindicated in children with viral illnesses due to risk of Reye's syndrome (hepatic failure + encephalopathy).
- C. ❌ Diphenhydramine (Benadryl) can be used cautiously for discomfort in some protocols — it is not contraindicated.
- D. ❌ Ibuprofen is safe for children with herpetic gingivostomatitis for pain and fever management.