Pharmacology · patient case question
Rivaroxaban, which the physician is considering adding, works by:
Patient case: Antihypertensive Review & Gingival Enlargement
demo: 60-year-old male
chief: “My gums have been growing over my front teeth.”
history: Hypertension, benign prostatic hyperplasia, angina.
meds: Nifedipine, prazosin, terazosin, atenolol
findings: Generalized fibrotic enlargement of the interdental papillae, most marked in the anterior maxilla. Plaque index moderate. No bone loss on bitewings.
Show answer and explanation
Correct answer: B. Selectively blocking the active site of factor Xa
- A. P2Y12 blockade is clopidogrel.
- B. Correct. Rivaroxaban, like apixaban, is a direct selective factor Xa inhibitor — an anticoagulant, not an antiplatelet.
- C. Direct thrombin inhibition is dabigatran.
- D. Irreversible COX-1 inhibition is aspirin.