Pathology · single question

A 16-year-old with methamphetamine use has mucosal pigmentation on the gingiva and palate. What is the MOST likely cause?

  1. Methamphetamine use
  2. Minocycline use
  3. Addison's disease
  4. Amalgam tattoo
Show answer and explanation

Correct answer: B. Minocycline use

Minocycline (a tetracycline antibiotic) causes systemic pigmentation of oral mucosa, bone, and teeth. It's commonly given to adolescents for acne. The pigmentation appears black/blue on gingiva and palate. Methamphetamine causes xerostomia and rampant caries ('meth mouth') but not mucosal pigmentation. Addison's causes diffuse pigmentation differently.

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