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Pathology · single question

Same case (Type IV reaction, 4 weeks later, target lesions). What is the specific type of lesion?

  1. Stevens-Johnson syndrome
  2. Epidermolysis bullosa
  3. Bullous pemphigoid
  4. Erythema multiforme
Show answer and explanation

Correct answer: A. Stevens-Johnson syndrome

  • A. Correct. Target lesions (concentric ring — red center, pale ring, red outer ring) are pathognomonic of Erythema multiforme, a Type IV hypersensitivity reaction often triggered by drugs or infections.
  • B. Incorrect. Stevens-Johnson syndrome is a severe mucocutaneous reaction with extensive epidermal detachment — more severe than classic EM.
  • C. Incorrect. Bullous pemphigoid shows tense bullae in elderly patients, not target lesions.
  • D. Incorrect. Epidermolysis bullosa is a genetic blistering disorder.

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