Pathology · single question

Which of the following is the most common oral manifestation in patients undergoing chemotherapy?

  1. Oral mucositis
  2. Osteonecrosis of the jaw
  3. Xerostomia
  4. Oral candidiasis
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Correct answer: A. Oral mucositis

Oral mucositis is the most common and dose-limiting oral complication of chemotherapy, affecting 40–80% of patients. Presents as painful erythema, ulceration, and mucosal sloughing.
  • A. CORRECT. Oral mucositis = most common oral complication of chemotherapy. Dose-dependent, affects rapidly dividing mucosal cells.
  • B. Osteonecrosis (MRONJ) is associated with bisphosphonates/antiangiogenics — not standard chemotherapy.
  • C. Xerostomia is prominent with head/neck radiation but secondary to mucositis in frequency for chemotherapy.
  • D. Candidiasis is frequent in immunocompromised chemo patients but is NOT the most common oral manifestation.

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