Pathology · patient case question

Which virus is involved?

Patient case: Case: facial palsy with an ipsilateral rash

Scenario: The case describes unilateral facial paralysis accompanied by a vesicular rash on the same side.

  1. Cytomegalovirus (HHV-5)
  2. Herpes simplex virus type 1 (HHV-1)
  3. Varicella zoster virus (HHV-3)
  4. Epstein-Barr virus (HHV-4)
Show answer and explanation

Correct answer: C. Varicella zoster virus (HHV-3)

  • A. CMV causes disease mainly in the immunocompromised and in congenital infection; it does not produce this picture.
  • B. HSV-1 is implicated in idiopathic Bell palsy, but Bell palsy has no rash. The rash is what makes this zoster.
  • C. Correct. Facial palsy with a vesicular rash in the ear or on the same side of the face is Ramsay Hunt syndrome — reactivation of varicella zoster in the geniculate ganglion.
  • D. EBV causes infectious mononucleosis, hairy leukoplakia and nasopharyngeal carcinoma — not a dermatomal vesicular rash with palsy.

Note: Ramsay Hunt carries a worse prognosis for recovery than Bell palsy, so prompt antiviral plus corticosteroid therapy matters.

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