Pathology · single question

A 7-year-old presents with bilateral bony swelling of the mandible. What is the MOST likely diagnosis?

  1. Cherubism
  2. Fibrous dysplasia
  3. Burkitt lymphoma
  4. Central giant cell granuloma
Show answer and explanation

Correct answer: A. Cherubism

  • A. Correct. Cherubism is a hereditary condition (autosomal dominant, chromosome 4p16) causing bilateral, symmetric enlargement of the mandible in children, giving a 'cherub' appearance. Classic diagnosis for bilateral jaw swelling in a young child.
  • B. Incorrect. Fibrous dysplasia typically presents as unilateral, painless expansion with a ground-glass radiographic appearance.
  • C. Incorrect. Burkitt lymphoma is associated with immunocompromised states and has systemic findings — not the classic bilateral symmetric jaw presentation of cherubism.
  • D. Incorrect. Central giant cell granuloma is typically unilateral, well-defined, and anterior — not bilateral symmetric swelling.

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