Pharmacology · single question

Which of the following is NOT a potential adverse effect of Lisinopril therapy?

  1. Hyperkalemia
  2. Persistent dry cough
  3. Hypoglycemia
  4. Acute kidney injury
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Correct answer: C. Hypoglycemia

Lisinopril (ACE inhibitor) adverse effects include: Hyperkalemia (decreased aldosterone → K retention — A is real), Persistent dry cough (bradykinin accumulation — B is real and very classic), Acute kidney injury (especially with bilateral renal artery stenosis — D is real), and Angioedema. HYPOGLYCEMIA is NOT a known effect of ACE inhibitors — that is associated with insulin, sulfonylureas, etc. Interestingly, some studies show ACE inhibitors may slightly improve insulin sensitivity, but hypoglycemia is NOT a listed adverse effect. C is the correct 'NOT' answer.

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