Pharmacology · single question
Which of the following is NOT a potential adverse effect of Lisinopril therapy?
Show answer and explanation
Correct answer: C. Hypoglycemia
Lisinopril (ACE inhibitor) adverse effects include: Hyperkalemia (decreased aldosterone → K retention — A is real), Persistent dry cough (bradykinin accumulation — B is real and very classic), Acute kidney injury (especially with bilateral renal artery stenosis — D is real), and Angioedema. HYPOGLYCEMIA is NOT a known effect of ACE inhibitors — that is associated with insulin, sulfonylureas, etc. Interestingly, some studies show ACE inhibitors may slightly improve insulin sensitivity, but hypoglycemia is NOT a listed adverse effect. C is the correct 'NOT' answer.