Pharmacology · single question

All of the following antibiotics are considered safe in pregnancy EXCEPT:

  1. Clindamycin
  2. Azithromycin
  3. Tetracycline
  4. Erythromycin
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Correct answer: C. Tetracycline

  • A. Clindamycin (FDA Category B) is considered safe in pregnancy and is the standard alternative for penicillin-allergic pregnant patients.
  • B. Azithromycin (FDA Category B) is considered safe in pregnancy and is commonly used for atypical respiratory infections.
  • C. Tetracycline is CONTRAINDICATED in pregnancy (FDA Category D). It chelates calcium, causing permanent staining and hypoplasia of developing teeth, and can cause maternal hepatotoxicity.
  • D. Erythromycin base (FDA Category B) is generally considered safe in pregnancy.

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