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Pharmacology · single question

A patient taking estradiol (oral contraceptive) needs antibiotics for a dental extraction. Which of the following statements about antibiotics is the EXCEPTION (not true)?

  1. Antibiotics commonly cause gastrointestinal disturbances
  2. Antibiotics can hinder analgesic efficacy
  3. Antibiotics can cause allergic reactions
  4. Antibiotics can reduce contraception efficacy
Show answer and explanation

Correct answer: B. Antibiotics can hinder analgesic efficacy

  • A. ❌ Antibiotics COMMONLY cause GI disturbances (nausea, diarrhea, dysbiosis) — TRUE.
  • B. ✅ Correct (exception). Antibiotics do NOT hinder analgesic efficacy. There is no known mechanism by which antibiotics interfere with pain medication action. This is the FALSE statement.
  • C. ❌ Antibiotics CAN cause allergic reactions — TRUE.
  • D. ❌ Antibiotics CAN potentially reduce OCP efficacy (gut flora changes affecting estrogen recirculation) — TRUE.

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