Pharmacology · single question

What is the mechanism of action of allopurinol (used for gout)?

  1. Uricosuric (increases uric acid excretion)
  2. Xanthine oxidase inhibitor
  3. COX inhibitor
  4. Anti-inflammatory microtubule inhibitor
Show answer and explanation

Correct answer: B. Xanthine oxidase inhibitor

  • A. Uricosurics (e.g., probenecid) increase excretion; allopurinol works differently.
  • B. Correct. Allopurinol inhibits xanthine oxidase, decreasing uric acid production.
  • C. COX inhibition describes NSAIDs.
  • D. Microtubule inhibition describes colchicine, not allopurinol.

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