Pharmacology · single question
Which of the following is a symptom of penicillin allergy?
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Correct answer: B. Stevens-Johnson Syndrome
- A. Nausea and vomiting are common SIDE EFFECTS of penicillin but are not immune-mediated ALLERGIC reactions — they are adverse effects, not allergic responses.
- B. Stevens-Johnson Syndrome (SJS) is a severe, life-threatening Type IV (delayed) hypersensitivity reaction that can occur with penicillin and other antibiotics (sulfonamides, NSAIDs). It involves extensive mucocutaneous necrosis and is a true ALLERGIC manifestation.
- C. Headache is not a classic manifestation of penicillin allergy.
- D. Diarrhea is a common side effect/adverse event from penicillin (disruption of gut flora) — it is not an immune-mediated allergic reaction.