Pharmacology · single question

Which of the following drugs does NOT typically cause xerostomia (dry mouth)?

  1. Amitriptyline
  2. Diphenhydramine
  3. Atropine
  4. Zoledronate
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Correct answer: D. Zoledronate

  • A. Tricyclic antidepressants strongly cause dry mouth (anticholinergic).
  • B. Antihistamines like diphenhydramine cause dry mouth (anticholinergic).
  • C. Atropine is a classic anticholinergic causing marked xerostomia.
  • D. Correct. Zoledronate (a bisphosphonate) is not anticholinergic and does not characteristically cause xerostomia.

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