Pharmacology · single question

Which of the following bacteria are resistant to clindamycin?

  1. Pseudomonas aeruginosa
  2. Fusobacterium species
  3. Streptococcus species
  4. Staphylococcus aureus
Show answer and explanation

Correct answer: A. Pseudomonas aeruginosa

Clindamycin has good coverage against most anaerobes (like Fusobacterium) and many Gram-positive cocci (Streptococcus, and many Staphylococcus aureus strains, including some MRSA), but it has essentially no useful activity against Gram-negative aerobic rods like Pseudomonas aeruginosa, which is intrinsically resistant.

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