Pathology · single question

What type of biopsy is most appropriate for a hairy tongue lesion?

  1. Exfoliative cytology
  2. Excisional biopsy
  3. Incisional biopsy
  4. Direct immunofluorescence biopsy
Show answer and explanation

Correct answer: B. Excisional biopsy

  • A. ❌ Exfoliative cytology is used for superficial surface cells — inadequate for a papillary tongue lesion requiring histological diagnosis.
  • B. ✅ Correct. For a small, discrete tongue lesion suspected to be hairy tongue, EXCISIONAL BIOPSY (complete removal) is appropriate — it is both diagnostic AND therapeutic.
  • C. ❌ Incisional biopsy takes a representative portion — used for large lesions not amenable to complete excision.
  • D. ❌ Direct immunofluorescence is used for vesiculobullous autoimmune conditions, not hairy tongue.

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