Pathology · single question

GERD (Gastroesophageal reflux disease) is primarily caused by dysfunction of which structure?

  1. Ileocecal valve
  2. Lower esophageal sphincter (LES)
  3. Upper esophageal sphincter
  4. Pyloric sphincter
Show answer and explanation

Correct answer: B. Lower esophageal sphincter (LES)

GERD = dysfunction/weakness of the lower esophageal sphincter (LES) → gastric acid refluxes into esophagus. Dental relevance: causes palatal erosion on maxillary anterior teeth. Source confirms: 'GERD is caused by: Lower esophageal sphincter.'
  • A. Ileocecal valve separates small/large intestine — not involved in GERD.
  • B. CORRECT. LES dysfunction → GERD → acid reflux. Causes palatal erosion in dental patients.
  • C. Upper esophageal sphincter dysfunction causes swallowing difficulties — not GERD.
  • D. Pyloric sphincter dysfunction = pyloric stenosis — not GERD.

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