Pathology · single question

What is the most common underlying cause of a ranula?

  1. Sialolith obstructing the duct
  2. Trauma to the sublingual gland/duct causing mucus extravasation
  3. Bacterial infection of the gland
  4. A salivary gland neoplasm
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Correct answer: B. Trauma to the sublingual gland/duct causing mucus extravasation

Most ranulas arise from trauma to the sublingual gland or its ducts of Rivinus, causing mucus to extravasate into surrounding tissue and form a pseudocyst (mucus extravasation phenomenon). Sialolith-related ductal obstruction is a less common (<10%) cause, typically producing a true epithelial-lined retention cyst rather than an extravasation pseudocyst.

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