Pathology · single question
A butterfly-shaped facial rash across cheeks and nose. Most likely diagnosis?
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Correct answer: C. Systemic lupus erythematosus (SLE)
Malar butterfly rash (erythema across cheeks and nasal bridge, sparing nasolabial folds) is classic for SLE (~50% of patients). Rosacea = telangiectasias and pustules centered on nose/cheeks. Dermatomyositis = heliotrope rash around eyes.