Pathology · single question

A butterfly-shaped facial rash across cheeks and nose. Most likely diagnosis?

  1. Dermatomyositis
  2. Rosacea
  3. Systemic lupus erythematosus (SLE)
  4. Sarcoidosis
Show answer and explanation

Correct answer: C. Systemic lupus erythematosus (SLE)

Malar butterfly rash (erythema across cheeks and nasal bridge, sparing nasolabial folds) is classic for SLE (~50% of patients). Rosacea = telangiectasias and pustules centered on nose/cheeks. Dermatomyositis = heliotrope rash around eyes.

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