Pharmacology · single question

What is the mechanism of action of carbamazepine?

  1. ACE inhibitor
  2. Beta-adrenergic blocker
  3. Calcium channel blocker
  4. Voltage-gated sodium channel blocker
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Correct answer: A. ACE inhibitor

  • A. Correct. Carbamazepine blocks voltage-gated sodium channels in a use-dependent manner, stabilizing neuronal membranes and preventing repetitive firing. Effective for trigeminal neuralgia and epilepsy.
  • B. Incorrect. Calcium channel blockers are a different class (gabapentin/pregabalin have a partial calcium mechanism).
  • C. Incorrect. Beta blockers affect adrenergic receptors, not ion channels.
  • D. Incorrect. ACE inhibitors are antihypertensives, not anticonvulsants.

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