Pathology · single question

Hard nodule-like lesions in the anterior floor of mouth or labial vestibule. What would a biopsy most likely reveal?

  1. Abscess
  2. Normal mucosa with fibrous connective tissue
  3. Minor salivary gland tissue (mucous acini)
  4. Squamous cell carcinoma
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Correct answer: C. Minor salivary gland tissue (mucous acini)

Hard, nodular lesions in the anterior labial mucosa or floor of the mouth can represent minor salivary gland pathology. Minor salivary glands are distributed throughout the oral mucosa (except the attached gingiva and anterior hard palate). Conditions affecting them include mucoceles, retention cysts, salivary gland tumors (benign or malignant), and necrotizing sialometaplasia. A biopsy of what appears to be normal-appearing tissue in this region would reveal mucous acini (the secretory units of minor salivary glands). This is relevant when evaluating lesions that could be mucoceles or salivary gland neoplasms.

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