Pharmacology · single question
During anaphylaxis in the dental office, what is the DRUG OF CHOICE and its dose?
Show answer and explanation
Correct answer: A. Epinephrine 0.3 mg (1:1,000) IM — anterolateral thigh
✓ A) Epinephrine 0.3 mg (1:1,000) IM is correct.
Anaphylaxis management: FIRST AND ONLY IMMEDIATE TREATMENT is epinephrine 0.3 mg of 1:1,000 concentration injected INTRAMUSCULARLY into the anterolateral thigh (through clothing if necessary). Children: 0.15 mg. Can repeat every 5–15 minutes. THEN call 911. THEN diphenhydramine + corticosteroids (secondary measures, do NOT delay epinephrine for these). Note: The PDF mentions 0.03 mg which appears to be a typo — the correct dose is 0.3 mg. Local dental anesthetic epinephrine (1:100,000) is much more dilute.
Anaphylaxis management: FIRST AND ONLY IMMEDIATE TREATMENT is epinephrine 0.3 mg of 1:1,000 concentration injected INTRAMUSCULARLY into the anterolateral thigh (through clothing if necessary). Children: 0.15 mg. Can repeat every 5–15 minutes. THEN call 911. THEN diphenhydramine + corticosteroids (secondary measures, do NOT delay epinephrine for these). Note: The PDF mentions 0.03 mg which appears to be a typo — the correct dose is 0.3 mg. Local dental anesthetic epinephrine (1:100,000) is much more dilute.