Pharmacology · single question
An epileptic patient takes hydrochlorothiazide and phenytoin. He is most likely to experience which oral side effect?
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Correct answer: B. Gingival enlargement (hyperplasia)
Three classic drugs cause gingival enlargement: phenytoin (anticonvulsant), cyclosporine (immunosuppressant), and calcium channel blockers (nifedipine, amlodipine). Good plaque control can minimize severity; gingivectomy may be needed in severe cases.