Pharmacology · single question
Mechanism of action of ibuprofen?
Show answer and explanation
Correct answer: C. REVERSIBLE cyclooxygenase (COX) inhibitor
- A. Incorrect. 5-LOX produces leukotrienes; NSAIDs like ibuprofen do not act there.
- B. Incorrect. Phospholipase A2 is inhibited by corticosteroids, not ibuprofen.
- C. Correct. Ibuprofen is a non-selective, REVERSIBLE inhibitor of COX-1/COX-2, reducing prostaglandin synthesis.
- D. Incorrect. ASPIRIN is the irreversible COX inhibitor; ibuprofen's inhibition is reversible/competitive.