Pharmacology · single question

A patient takes allopurinol, naproxen, metoprolol and an antidepressant. Which drug most likely causes his dyspepsia?

  1. Metoprolol
  2. None of these cause dyspepsia
  3. Allopurinol
  4. The antidepressant
Show answer and explanation

Correct answer: C. Allopurinol

  • A. Metoprolol causes fatigue, bradycardia and bronchospasm rather than prominent dyspepsia.
  • B. Several of these agents can affect the GI tract.
  • C. Allopurinol commonly causes GI upset including nausea and dyspepsia, and it also carries a risk of severe cutaneous reactions.
  • D. SSRIs can cause nausea, but dyspepsia is less characteristic.

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