Pharmacology · single question

A patient on corticosteroid medication is at increased risk for which complication during dental procedures?

  1. Adrenal insufficiency/adrenal crisis under stress
  2. Neuroleptic malignant syndrome
  3. Malignant hyperthermia
  4. Respiratory depression from local anesthetic
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Correct answer: A. Adrenal insufficiency/adrenal crisis under stress

  • A. Correct. Long-term corticosteroid use suppresses the hypothalamic-pituitary-adrenal (HPA) axis, causing adrenal insufficiency. Under the physiologic stress of dental procedures, the patient cannot mount a normal cortisol stress response, risking an adrenal crisis (hypotension, weakness, nausea, cardiovascular collapse). Steroid supplementation may be needed.
  • B. Neuroleptic malignant syndrome is related to antipsychotic medications — not corticosteroids.
  • C. Malignant hyperthermia is triggered by volatile anesthetic agents — not related to corticosteroids or dental procedures.
  • D. Local anesthetics do not cause respiratory depression under corticosteroid use.

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