Micro & Immunology · single question

A patient has a peptic ulcer. Which microorganism is most responsible for peptic ulcer disease?

  1. Candida albicans
  2. Escherichia coli
  3. Helicobacter pylori
  4. Streptococcus mutans
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Correct answer: C. Helicobacter pylori

  • A. Candida albicans is a fungus that causes oral/esophageal candidiasis, not peptic ulcers.
  • B. E. coli causes urinary/GI infections, not peptic ulcers.
  • C. Correct. Helicobacter pylori, a gram-negative spiral bacterium, is the leading cause of peptic (gastric/duodenal) ulcers; the other major cause is chronic NSAID use.
  • D. S. mutans is the principal cariogenic oral bacterium — unrelated to gastric ulcers.

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