Micro & Immunology · single question
A patient develops a delayed (days-later) allergic skin reaction to celecoxib. This reaction is mediated by:
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Correct answer: A. T cells (Type IV, delayed hypersensitivity)
- A. Correct. A delayed reaction appearing days later is T-cell-mediated (Type IV) hypersensitivity.
- B. IgE-mediated (Type I) reactions are immediate (minutes), e.g., anaphylaxis/urticaria.
- C. Type II involves antibody-mediated cytotoxicity against cells.
- D. Type III involves circulating immune-complex deposition (e.g., serum sickness).
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