Micro & Immunology · single question

Same case (Type I allergic reaction). Which sign specifically identifies the allergic nature of the reaction?

  1. Rash (urticaria)
  2. Nausea
  3. Diarrhea
  4. Vomiting
Show answer and explanation

Correct answer: A. Rash (urticaria)

  • A. Correct. Rash/urticaria/hives is the hallmark dermatologic sign of IgE-mediated Type I hypersensitivity, reflecting mast cell degranulation and histamine release.
  • B. Incorrect. Nausea occurs in many conditions and is not specific to the allergic immune mechanism.
  • C. Incorrect. Diarrhea can result from GI mast cell activation but is not the specific identifying marker.
  • D. Incorrect. Vomiting is a non-specific GI response, not the distinctive allergic marker.

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