Pathology · single question

A 65-year-old woman with breast cancer diagnosed 2 years ago presents with bone loss noted on panoramic radiograph. What is the most likely diagnosis?

  1. Bone metastasis
  2. Ameloblastoma
  3. Odontogenic Keratocyst (OKC)
  4. Traumatic bone cyst
Show answer and explanation

Correct answer: A. Bone metastasis

✓ A) Bone metastasis is correct.
In a patient with a known malignancy (breast cancer), jaw bone loss should raise immediate suspicion for metastatic disease. Breast cancer commonly metastasizes to bone. The radiographic appearance of metastatic lesions can be radiolucent (osteolytic) or mixed. OKC, ameloblastoma, and traumatic bone cyst are primary jaw lesions unrelated to systemic malignancy.

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