Xerostomia (chronic dry mouth) is most associated with which oral complication?

Angular cheilitis (perleche) is a characteristic complication of xerostomia. Reduced saliva allows saliva to pool at the corners of the mouth (angular region), creating a moist environment that promotes Candida albicans and/or bacterial colonization. The angular commissures become erythematous, cracked, and painful. Angular cheilitis is associated with xerostomia, nutritional deficiencies (B12, iron, folate), ill-fitting dentures, and immune compromise.