Pathology · single question

A biopsy reveals Civatte bodies. Most appropriate treatment?

  1. Amoxicillin
  2. Clobetasol (topical corticosteroid)
  3. Clotrimazole
  4. Acyclovir
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Correct answer: B. Clobetasol (topical corticosteroid)

Civatte bodies (degenerated apoptotic keratinocytes at basement membrane) = hallmark of ORAL LICHEN PLANUS histology. Treatment: topical corticosteroids (clobetasol/fluocinonide/Lidex). Acyclovir = viral; amoxicillin = bacterial; clotrimazole = Candida.

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