Pathology · single question

A biopsy shows subepithelial clefting with linear IgG and complement deposition at the basement membrane. To which specialist should the patient be referred?

  1. Nephrologist
  2. Ophthalmologist
  3. Cardiologist
  4. Neurologist
Show answer and explanation

Correct answer: B. Ophthalmologist

  • A. Renal involvement is not part of this disease.
  • B. Correct. These findings define mucous membrane (cicatricial) pemphigoid. Ocular involvement causes symblepharon and progressive scarring that can lead to blindness — early ophthalmologic evaluation is essential.
  • C. Cardiac involvement is not a feature of mucous membrane pemphigoid.
  • D. Neurologic involvement is not characteristic.

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