Pathology · single question
A biopsy shows subepithelial clefting with linear IgG and complement deposition at the basement membrane. To which specialist should the patient be referred?
Show answer and explanation
Correct answer: B. Ophthalmologist
- A. Renal involvement is not part of this disease.
- B. Correct. These findings define mucous membrane (cicatricial) pemphigoid. Ocular involvement causes symblepharon and progressive scarring that can lead to blindness — early ophthalmologic evaluation is essential.
- C. Cardiac involvement is not a feature of mucous membrane pemphigoid.
- D. Neurologic involvement is not characteristic.