Pathology · patient case with 2 questions

Case: facial palsy with an ipsilateral rash

Scenario: The case describes unilateral facial paralysis accompanied by a vesicular rash on the same side.

Question 1

Which virus is involved?

  1. Cytomegalovirus (HHV-5)
  2. Herpes simplex virus type 1 (HHV-1)
  3. Varicella zoster virus (HHV-3)
  4. Epstein-Barr virus (HHV-4)
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Correct answer: C. Varicella zoster virus (HHV-3)

  • A. CMV causes disease mainly in the immunocompromised and in congenital infection; it does not produce this picture.
  • B. HSV-1 is implicated in idiopathic Bell palsy, but Bell palsy has no rash. The rash is what makes this zoster.
  • C. Correct. Facial palsy with a vesicular rash in the ear or on the same side of the face is Ramsay Hunt syndrome — reactivation of varicella zoster in the geniculate ganglion.
  • D. EBV causes infectious mononucleosis, hairy leukoplakia and nasopharyngeal carcinoma — not a dermatomal vesicular rash with palsy.

Note: Ramsay Hunt carries a worse prognosis for recovery than Bell palsy, so prompt antiviral plus corticosteroid therapy matters.

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Question 2

A patient is drooling and cannot close the eye on the affected side. All of the following may occur EXCEPT:

  1. Glaucoma
  2. Loss of the ability to raise the eyebrow on that side
  3. Corneal drying and exposure keratitis
  4. Drooping of the corner of the mouth with food pooling
Show answer and explanation

Correct answer: A. Glaucoma

  • A. Correct — this is the exception. Glaucoma results from raised intraocular pressure and has nothing to do with facial nerve function. The eye complication here is surface drying, not pressure.
  • B. This does occur, and it is the key distinction: a lower motor neuron lesion paralyses the forehead too. In a stroke the forehead is spared.
  • C. This does occur. Without a blink reflex the cornea dries and ulcerates, which is why these patients need lubricating drops, a patch, and often taping of the lid at night.
  • D. This does occur. Loss of buccinator and orbicularis oris tone lets the commissure droop and food collect in the vestibule.

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