Pathology · single question

Which type of biopsy is most appropriate?

  1. Incisional biopsy
  2. Excisional biopsy
  3. Biopsy of the areas of ulceration only
  4. Cytology (exfoliative)
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Correct answer: A. Incisional biopsy

Rules of biopsy: if the lesion is 1 cm, suspicious for malignancy, or fixed to deep tissues, perform an INCISIONAL biopsy to sample a representative portion for histopathology before definitive treatment. Excisional biopsy (B) is reserved for small benign-appearing lesions <1 cm. Biopsying only the ulcerated area (C) gives non-diagnostic necrotic tissue. Cytology (D) lacks the architectural detail needed to grade and stage a suspected carcinoma.

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