Pathology · single question
Which type of biopsy is most appropriate?
Show answer and explanation
Correct answer: A. Incisional biopsy
Rules of biopsy: if the lesion is 1 cm, suspicious for malignancy, or fixed to deep tissues, perform an INCISIONAL biopsy to sample a representative portion for histopathology before definitive treatment. Excisional biopsy (B) is reserved for small benign-appearing lesions <1 cm. Biopsying only the ulcerated area (C) gives non-diagnostic necrotic tissue. Cytology (D) lacks the architectural detail needed to grade and stage a suspected carcinoma.